A full reading of 185 public companies — the Nasdaq-100 plus every software name in the iShares IGV ETF — through Sequoia's autopilot thesis: who sells the shovels, who is migrating from tools to outcomes, who gets bypassed, and who is simply orthogonal. The IGV expansion adds 80 software-layer pure-plays where the services-as-software thesis bites hardest.
The Sequoia argument is straightforward: the next trillion-dollar company will not sell AI tools by the seat but AI outcomes by the job, capturing services budgets rather than software budgets. The question for a public-markets investor is where the Nasdaq-100 and the broader IGV software universe sit in that shift. Read across the combined index (185 names), a clean five-way sort emerges.
Pure enablers — NVIDIA, Broadcom, AWS, and the semiconductor-equipment names (ASML, LRCX, KLAC, AMAT) plus memory (Micron) — sit upstream of every autopilot and receive the tailwind regardless of which startup wins any given vertical. The cleanest thesis vehicles in the index.
Hybrid transitioners — Microsoft, Meta, Alphabet, Palantir, Shopify, Intuit, Workday, Adobe, Synopsys, Cadence — each straddle enabler and autopilot-builder roles. They have credible data moats, are visibly moving from seat pricing toward outcomes, and carry specific near-term risk tied to their legacy monetisation shape.
Autopilot-native businesses — Tesla's FSD-as-robotaxi, Palantir AIP, Shopify Sidekick, Axon Evidence.com — literally sell outcomes, not tools. Small in count, high in thesis purity.
Disruption-exposed incumbents — Cognizant, Thomson Reuters, ADP, Paychex, Intuit (dual exposure), PayPal, Charter/Comcast — where the services or tool revenue most directly overlaps with what autopilot startups are building toward. These are where the thesis bites hardest.
Orthogonal names — utilities, bottlers, railroads, retail staples, oilfield services, most biotech — sit largely outside the thesis perimeter. The framework applies weakly and verdict defaults to Neutral on thesis grounds; own them for other reasons.
Horizontal: picks-and-shovels exposure (Enabler score). Vertical: share of current revenue at risk of being bypassed by an autopilot. Bubble size: relative position in the Nasdaq-100 at the time this note was drafted — larger bubbles are the mega-caps. Only the top-15 anchors are labelled; hover any bubble for the full read.
Each company read along Sequoia's Intelligence-vs-Judgment axis, their current copilot and autopilot posture, the shape of their data moat, and the reach of their execution layer. Hover any badge for the rationale; click any company name for its memo.
| Company | Intel / Judgment | Copilot | Autopilot | Data moat | Execution layer | Verdict |
|---|---|---|---|---|---|---|
| NVDA
NVIDIA |
Not applicable | None | None | Strong | Not applicable | Highly Positive |
| AAPL
Apple |
Judgment-leaning | Strong | Emerging | Strong | Strong | Neutral |
| MSFT
Microsoft |
Mixed → Intelligence-leaning | Core | Emerging | Massive | Strong | Highly Positive |
| AMZN
Amazon |
Mixed | Strong | Emerging | Massive | Strong | Highly Positive |
| META
Meta Platforms |
Intelligence-leaning | Moderate | Emerging | Massive | Moderate | Positive |
| GOOGL
Alphabet |
Intelligence-heavy (Search) + Mixed (Workspace) | Strong | Emerging | Massive | Strong | Watch |
| TSLA
Tesla |
Intelligence-heavy (perception/planning) | Current | Core | Very Strong | Strongest | Positive |
| AVGO
Broadcom |
Not applicable | None | None | Moderate | Not applicable | Highly Positive |
| WMT
Walmart |
Mixed → Intelligence-leaning (internal) | Emerging | Emerging | Strong | Strong | Neutral |
| COST
Costco |
Not applicable | Minimal | Minimal | Moderate | Moderate | Neutral |
| ADBE
Adobe |
Intelligence-leaning | Core | Emerging | Strong | Strong | Watch |
| AMD
Advanced Micro Devices |
Not applicable | Core | Core | Limited | Not applicable | Positive |
| ABNB
Airbnb |
Mixed | Moderate | Limited | Strong | Limited | Positive |
| ALNY
Alnylam Pharmaceuticals |
Judgment-heavy | Emerging | None | Moderate | Not applicable | Neutral |
| AEP
American Electric Power |
Intelligence-leaning | Emerging | Minimal | Strong | Limited | Neutral |
| AMGN
Amgen |
Judgment-heavy | Emerging | None | Moderate | Not applicable | Neutral |
| ADI
Analog Devices |
Not applicable | Strong | Core | Limited | Not applicable | Positive |
| AMAT
Applied Materials |
Not applicable | Core | Core | Limited | Not applicable | Highly Positive |
| APP
AppLovin |
Intelligence-leaning | Moderate | Core | Very Strong | Strong | Watch |
| ARM
Arm Holdings |
Not applicable | Strong | Core | Limited | Not applicable | Positive |
| ASML
ASML Holding |
Not applicable | Core | Core | Limited | Not applicable | Highly Positive |
| TEAM
Atlassian |
Intelligence-leaning | Core | Moderate | Moderate | Moderate | Watch |
| ADSK
Autodesk |
Mixed | Core | Moderate | Strong | Strong | Watch |
| ADP
Automatic Data Processing |
Mixed | Strong | Strong | Massive | Strongest | Positive |
| AXON
Axon Enterprise |
Intelligence-leaning | Strong | Strong | Very Strong | Strong | Positive |
| BKR
Baker Hughes |
Mixed | Moderate | Emerging | Strong | Moderate | Watch |
| BKNG
Booking Holdings |
Intelligence-leaning | Strong | Limited | Very Strong | Moderate | Positive |
| CDNS
Cadence Design Systems |
Intelligence-heavy | Strong | Moderate | Strong | Strong | Positive |
| CHTR
Charter Communications |
Intelligence-leaning | Emerging | Limited | Moderate | Limited | Neutral |
| CTAS
Cintas |
Mixed | Emerging | Limited | Moderate | Limited | Neutral |
| CSCO
Cisco Systems |
Intelligence-leaning | Strong | Moderate | Strong | Strong | Watch |
| CCEP
Coca-Cola Europacific Partners |
Intelligence-leaning | Emerging | Minimal | Limited | Limited | Neutral |
| CTSH
Cognizant |
Mixed | Strong | Emerging | Limited | Moderate | Watch |
| CMCSA
Comcast |
Intelligence-leaning | Moderate | Limited | Strong | Limited | Neutral |
| CEG
Constellation Energy |
Intelligence-leaning | Emerging | Minimal | Strong | Limited | Neutral |
| CPRT
Copart |
Mixed | Moderate | Limited | Strong | Moderate | Neutral |
| CSGP
CoStar Group |
Intelligence-leaning | Moderate | Limited | Very Strong | Limited | Neutral |
| CRWD
CrowdStrike |
Intelligence-leaning | Strong | Core | Very Strong | Strong | Highly Positive |
| CSX
CSX Corporation |
Intelligence-leaning | Emerging | Minimal | Limited | Limited | Neutral |
| DDOG
Datadog |
Intelligence-heavy | Core | Strong | Strong | Strong | Positive |
| DXCM
Dexcom Inc. |
Intelligence-leaning | Strong | Emerging | Very Strong | Limited | Watch |
| FANG
Diamondback Energy Inc. |
Intelligence-leaning | Moderate | Limited | Moderate | None | Neutral |
| DASH
DoorDash Inc. |
Intelligence-heavy | Limited | Core | Very Strong | Strongest | Positive |
| EA
Electronic Arts Inc. |
Intelligence-leaning | Strong | None | Strong | None | Neutral |
| EXC
Exelon Corporation |
Intelligence-leaning | Moderate | Emerging | Moderate | Limited | Neutral |
| FAST
Fastenal Company |
Mixed | Moderate | Emerging | Moderate | Strong | Watch |
| FER
Ferrovial SE |
Intelligence-leaning | Moderate | Limited | Limited | None | Neutral |
| FTNT
Fortinet Inc. |
Intelligence-heavy | Strong | Moderate | Strong | Strong | Watch |
| GEHC
GE HealthCare Technologies Inc. |
Intelligence-heavy | Core | Emerging | Strong | Limited | Watch |
| GILD
Gilead Sciences Inc. |
Intelligence-leaning | Minimal | None | Moderate | Not applicable | Negative |
| HON
Honeywell International Inc. |
Intelligence-heavy | Strong | Strong | Very Strong | Strongest | Positive |
| IDXX
Idexx Laboratories Inc. |
Intelligence-heavy | Strong | Moderate | Strong | Limited | Watch |
| INSM
Insmed Incorporated |
Intelligence-leaning | Minimal | None | Limited | Not applicable | Neutral |
| INTC
Intel Corporation |
Not applicable | None | None | Moderate | None | Watch |
| INTU
Intuit Inc. |
Intelligence-heavy | Strong | Core | Massive | Strongest | Positive |
| ISRG
Intuitive Surgical Inc. |
Judgment-heavy | Strong | Core | Strong | Strongest | Highly Positive |
| KDP
Keurig Dr Pepper Inc. |
Not applicable | None | None | None | None | Neutral |
| KLAC
KLA Corporation |
Not applicable | Strong | Limited | Very Strong | Limited | Positive |
| KHC
Kraft Heinz Company |
Not applicable | None | None | None | None | Neutral |
| LRCX
Lam Research Corporation |
Not applicable | Moderate | Limited | Very Strong | Limited | Positive |
| LIN
Linde PLC |
Intelligence-leaning | Moderate | Limited | Moderate | None | Neutral |
| MAR
Marriott International Inc. |
Mixed | Moderate | Moderate | Strong | Strong | Watch |
| MRVL
Marvell Technology Inc. |
Not applicable | None | None | Moderate | None | Positive |
| MELI
Mercado Libre Inc. |
Intelligence-heavy | Strong | Core | Very Strong | Strongest | Positive |
| MCHP
Microchip Technology Inc. |
Not applicable | None | None | Limited | None | Neutral |
| MU
Micron Technology Inc. |
Not applicable | None | None | Strong | None | Positive |
| MSTR
MicroStrategy Inc. |
Not applicable | Moderate | None | Limited | None | Negative |
| MDLZ
Mondelez International Inc. |
Not applicable | None | None | None | None | Neutral |
| MPWR
Monolithic Power Systems Inc. |
Not applicable | None | None | Limited | None | Neutral |
| MNST
Monster Beverage Corporation |
Not applicable | None | None | None | None | Neutral |
| NFLX
Netflix Inc. |
Intelligence-heavy | Strong | Limited | Massive | Moderate | Neutral |
| NXPI
NXP Semiconductors |
Intelligence-heavy | Limited | Emerging | Moderate | Limited | Watch |
| ORLY
O'Reilly Automotive |
Intelligence-heavy | Emerging | Limited | Moderate | Limited | Neutral |
| ODFL
Old Dominion Freight Line |
Mixed | Moderate | Emerging | Strong | Strong | Watch |
| PCAR
PACCAR |
Intelligence-leaning | Moderate | Emerging | Strong | Strong | Watch |
| PLTR
Palantir Technologies |
Intelligence-heavy | Moderate | Core | Massive | Strongest | Highly Positive |
| PANW
Palo Alto Networks |
Intelligence-heavy | Strong | Moderate | Very Strong | Moderate | Watch |
| PAYX
Paychex |
Intelligence-leaning | Moderate | Emerging | Moderate | Moderate | Watch |
| PYPL
PayPal |
Intelligence-heavy | Limited | Moderate | Strong | Moderate | Negative |
| PDD
PDD Holdings |
Intelligence-leaning | Strong | Moderate | Massive | Moderate | Negative |
| PEP
PepsiCo |
Intelligence-heavy | Limited | Moderate | Moderate | Limited | Neutral |
| QCOM
Qualcomm |
Intelligence-heavy | Limited | Emerging | Moderate | Limited | Positive |
| REGN
Regeneron Pharmaceuticals |
Intelligence-heavy | Moderate | Limited | Strong | Moderate | Watch |
| ROP
Roper Technologies |
Intelligence-leaning | Moderate | Moderate | Moderate | Moderate | Watch |
| ROST
Ross Stores |
Intelligence-heavy | Emerging | Limited | Moderate | Limited | Neutral |
| STX
Seagate Technology |
Not applicable | None | Limited | Limited | None | Neutral |
| SHOP
Shopify |
Intelligence-heavy | Strong | Core | Massive | Strongest | Highly Positive |
| SBUX
Starbucks |
Intelligence-heavy | Limited | Emerging | Moderate | Limited | Neutral |
| SNPS
Synopsys |
Intelligence-heavy | Moderate | Strong | Very Strong | Strong | Positive |
| TMUS
T-Mobile US |
Intelligence-leaning | Emerging | Emerging | Very Strong | Moderate | Neutral |
| TTWO
Take-Two Interactive |
Mixed | Moderate | Limited | Moderate | Limited | Neutral |
| TXN
Texas Instruments |
Intelligence-heavy | Limited | Emerging | Moderate | Limited | Watch |
| TRI
Thomson Reuters |
Intelligence-heavy | Strong | Emerging | Very Strong | Moderate | Positive |
| VRSK
Verisk Analytics |
Intelligence-heavy | Moderate | Emerging | Strong | Moderate | Watch |
| VRTX
Vertex Pharmaceuticals |
Intelligence-heavy | Limited | Limited | Strong | Moderate | Watch |
| WBD
Warner Bros. Discovery |
Intelligence-leaning | Limited | Emerging | Strong | Limited | Neutral |
| WDC
Western Digital |
Not applicable | None | Limited | Limited | None | Neutral |
| WDAY
Workday |
Intelligence-heavy | Strong | Emerging | Massive | Strong | Positive |
| XEL
Xcel Energy |
Intelligence-heavy | Limited | Emerging | Moderate | Limited | Neutral |
| ZS
Zscaler |
Intelligence-heavy | Strong | Emerging | Very Strong | Moderate | Watch |
| CRM
Salesforce Inc. |
Judgment-heavy | Strong | Core | Massive | Strongest | Positive |
| NOW
ServiceNow, Inc. |
Mixed | Core | Strong | Massive | Strongest | Positive |
| FIG
Figma, Inc. |
Mixed | Core | Emerging | Real but contested | Strong | Watch |
| SE
Sea Limited |
Mixed | Internal | Emerging | Regional | Strong | Positive |
| GRAB
Grab Holdings Limited |
Intelligence-heavy | Internal | Core | Regional | Strong | Positive |
| ORCL
Oracle |
Mixed | Moderate | Emerging | Strong | Strong | Highly Positive |
| FICO
Fair Isaac |
Intelligence-heavy | Emerging | Core | Strong | Strong | Highly Positive |
| ZM
Zoom Communications |
Intelligence-leaning | Core | Emerging | Moderate | Strong | Watch |
| PTC
PTC Inc. |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Positive |
| TRMB
Trimble |
Intelligence-leaning | Moderate | Core | Strong | Strong | Positive |
| TYL
Tyler Technologies |
Mixed | Emerging | Limited | Strong | Strong | Positive |
| GWRE
Guidewire Software |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Positive |
| HUBS
HubSpot |
Intelligence-leaning | Core | Strong | Moderate | Strong | Positive |
| GEN
Gen Digital |
Intelligence-heavy | Emerging | Core | Strong | Strong | Positive |
| NTNX
Nutanix |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| DT
Dynatrace |
Intelligence-heavy | Strong | Core | Strong | Strong | Positive |
| IOT
Samsara |
Intelligence-heavy | Moderate | Strong | Strong | Strong | Positive |
| IDCC
InterDigital |
Not applicable | None | None | Moderate | Limited | Positive |
| DOCU
Docusign |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Watch |
| U
Unity Software |
Intelligence-leaning | Moderate | Limited | Moderate | Strong | Watch |
| RBRK
Rubrik |
Intelligence-leaning | Moderate | Strong | Strong | Strong | Positive |
| MANH
Manhattan Associates |
Intelligence-heavy | Moderate | Strong | Strong | Strong | Positive |
| CWAN
Clearwater Analytics |
Intelligence-heavy | Emerging | Strong | Strong | Strong | Positive |
| SNAP
Snap Inc. |
Intelligence-leaning | Strong | Moderate | Strong | Strong | Watch |
| DSGX
Descartes Systems Group |
Intelligence-leaning | Emerging | Strong | Strong | Strong | Positive |
| AUR
Aurora Innovation |
Intelligence-heavy | None | Core | Strong | Strong | Positive |
| PCOR
Procore Technologies |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| CRCL
Circle Internet Group |
Intelligence-leaning | Emerging | Emerging | Limited | Strong | Positive |
| OTEX
OpenText |
Intelligence-leaning | Emerging | Limited | Strong | Moderate | Watch |
| BSY
Bentley Systems |
Intelligence-heavy | Strong | Emerging | Strong | Strong | Positive |
| S
SentinelOne |
Intelligence-heavy | Strong | Core | Strong | Strong | Positive |
| YOU
Clear Secure |
Mixed | Limited | Strong | Strong | Strong | Watch |
| PATH
UiPath |
Intelligence-heavy | Strong | Core | Moderate | Strong | Positive |
| ACIW
ACI Worldwide |
Intelligence-heavy | Moderate | Emerging | Strong | Strong | Positive |
| ESTC
Elastic |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| DBX
Dropbox |
Intelligence-leaning | Moderate | Limited | Moderate | Moderate | Watch |
| CVLT
Commvault |
Intelligence-heavy | Moderate | Emerging | Moderate | Strong | Positive |
| PEGA
Pegasystems |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Watch |
| DLB
Dolby Laboratories |
Intelligence-leaning | Limited | Emerging | Strong | Moderate | Watch |
| APPF
AppFolio |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| LIF
Life360 |
Mixed | Limited | Emerging | Moderate | Moderate | Watch |
| TTAN
ServiceTitan |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Positive |
| ZETA
Zeta Global |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Positive |
| BOX
Box |
Intelligence-leaning | Strong | Emerging | Moderate | Moderate | Positive |
| BILL
BILL Holdings |
Intelligence-heavy | Strong | Emerging | Moderate | Strong | Positive |
| CCC
CCC Intelligent Solutions |
Intelligence-heavy | Strong | Strong | Strong | Strong | Highly Positive |
| QTWO
Q2 Holdings |
Intelligence-leaning | Moderate | Emerging | Moderate | Strong | Positive |
| GTLB
GitLab |
Intelligence-heavy | Strong | Emerging | Moderate | Strong | Positive |
| ADEA
Adeia |
Not applicable | Not applicable | Not applicable | Moderate | Not applicable | Neutral |
| RNG
RingCentral |
Intelligence-leaning | Strong | Emerging | Moderate | Moderate | Watch |
| WK
Workiva |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| QLYS
Qualys |
Intelligence-heavy | Moderate | Emerging | Strong | Strong | Positive |
| SOUN
SoundHound AI |
Intelligence-heavy | Limited | Strong | Moderate | Moderate | Watch |
| VRNS
Varonis Systems |
Intelligence-heavy | Moderate | Emerging | Moderate | Strong | Positive |
| KVYO
Klaviyo |
Intelligence-heavy | Core | Emerging | Strong | Strong | Positive |
| BB
BlackBerry |
Mixed | Limited | Emerging | Moderate | Moderate | Watch |
| TDC
Teradata |
Intelligence-leaning | Moderate | Limited | Moderate | Moderate | Watch |
| ALRM
Alarm.com |
Intelligence-leaning | Moderate | Emerging | Moderate | Strong | Positive |
| TENB
Tenable |
Intelligence-heavy | Moderate | Emerging | Strong | Strong | Positive |
| BRZE
Braze |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| SPSC
SPS Commerce |
Intelligence-leaning | Moderate | Emerging | Strong | Strong | Positive |
| NCNO
nCino |
Intelligence-leaning | Moderate | Emerging | Moderate | Strong | Watch |
| NN
NextNav |
Not applicable | Not applicable | Not applicable | Moderate | Not applicable | Neutral |
| ATEN
A10 Networks |
Intelligence-leaning | Limited | Emerging | Moderate | Moderate | Neutral |
| RAMP
LiveRamp |
Intelligence-leaning | Moderate | Emerging | Strong | Strong | Positive |
| FRSH
Freshworks |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Positive |
| AGYS
Agilysys |
Mixed | Moderate | Emerging | Moderate | Strong | Positive |
| BL
BlackLine |
Intelligence-leaning | Strong | Strong | Moderate | Strong | Positive |
| AVPT
AvePoint |
Intelligence-leaning | Moderate | Emerging | Moderate | Strong | Positive |
| ALKT
Alkami Technology |
Intelligence-leaning | Moderate | Emerging | Moderate | Strong | Positive |
| BLKB
Blackbaud |
Mixed | Moderate | Limited | Moderate | Strong | Watch |
| INTA
Intapp |
Intelligence-leaning | Strong | Emerging | Strong | Strong | Positive |
| PRGS
Progress Software |
Mixed | Limited | Limited | Moderate | Moderate | Neutral |
| FIVN
Five9 |
Intelligence-leaning | Strong | Strong | Moderate | Strong | Positive |
| LSPD
Lightspeed Commerce |
Mixed | Moderate | Emerging | Moderate | Moderate | Watch |
| AI
C3.ai |
Intelligence-heavy | Moderate | Emerging | Limited | Moderate | Watch |
| VYX
NCR Voyix |
Mixed | Moderate | Emerging | Moderate | Strong | Watch |
| VERX
Vertex, Inc. |
Intelligence-leaning | Moderate | Emerging | Strong | Strong | Positive |
| APPN
Appian |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Watch |
| CXM
Sprinklr |
Intelligence-leaning | Strong | Emerging | Moderate | Strong | Watch |
| PD
PagerDuty |
Intelligence-heavy | Strong | Emerging | Moderate | Strong | Positive |
| PAR
PAR Technology |
Mixed | Moderate | Emerging | Moderate | Strong | Positive |
| SEMR
Semrush |
Intelligence-leaning | Strong | Emerging | Strong | Moderate | Watch |
| ASAN
Asana |
Intelligence-leaning | Strong | Emerging | Moderate | Moderate | Watch |
| QBTS
D-Wave Quantum |
Not applicable | Not applicable | Not applicable | Moderate | Not applicable | Neutral |
185 names — Nasdaq-100 plus every IGV software holding. Controls above filter both the matrix and this list together. Click any company for the full memo.